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depo-subQ provera 104
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The depo-subQ provera 104 Q and A

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Frequently Asked Questions About depo-subQ provera 104

Remember, your healthcare provider is the best person to answer all your questions. Only your healthcare provider can tell you if depo-subQ provera 104 is right for you.

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What is depo-subQ provera 104?

depo-subQ provera 104 is an injectable form of birth control. It is also indicated for management of endometriosis-associated pain. Symptoms of endometriosis arise when cells normally inside your uterus grow outside the uterus. The cells respond to hormones, and may cause painful periods, pelvic pain, and painful sex.

What is in depo-subQ provera 104?

The active ingredient is medroxyprogesterone acetate. Inactive ingredients are: methylparaben, propylparaben, sodium chloride, polyethylene glycol, polysorbate 80, monobasic sodium phosphate H2O, dibasic sodium phosphate 12H2O, methionine, povidone, water for shot. When necessary, the pH is adjusted with sodium hydroxide or hydrochloric acid, or both.

What’s the most important information I should know about depo-subQ provera 104?

depo-subQ provera 104 is a drug for birth control. It is also indicated for management of endometriosis-associated pain.

IMPORTANT SAFETY INFORMATION

Using depo-subQ provera 104 may cause you to lose calcium stored in your bones.
The longer you use depo-subQ provera 104, the more calcium you are likely to lose. The lost calcium may not return completely once you stop using depo-subQ provera 104.
Loss of calcium may cause weak, porous bones (osteoporosis) that could increase the risk that your bones might break, especially after menopause. It is not known whether your risk of developing osteoporosis may be greater if you are a teenager when you start to use depo-subQ provera 104.
You should use depo-subQ provera 104 long-term (for example, more than 2 years) only if other methods of birth control are not right for you.

depo-subQ provera 104 does not protect you from HIV (AIDS) and other diseases spread through sex (STDs).

Do not take depo-subQ provera 104 if you are pregnant or might be pregnant, if you have any unexplained vaginal bleeding, have ever had breast cancer, have ever had serious blood clots, such as blood clots in your legs, lungs, heart, or brain, have liver disease, or are allergic to anything in depo-subQ provera 104.

In addition to loss of calcium from your bones, other serious risks include abnormal or very heavy bleeding, liver problems, and allergic reactions such as hives, problems breathing, or not feeling right after the shot. If you have sharp chest pain, cough blood, suddenly have trouble breathing, have a sudden severe headache with vomiting, blindness, trouble talking, weakness, numbness in an arm or leg, get dizzy or faint, or have swelling or severe pain in your leg, you may have a serious blood clot and should call your healthcare provider immediately.

The most common side effects with depo-subQ provera 104 are changes in your monthly period, weight gain of an average of 3 to 4 pounds during the first year, a skin reaction where you got the shot, and headache.

How is depo-subQ provera 104 different from Depo-Provera CI 150?

The depo-subQ provera 104 needle is smaller than the one used for Depo-Provera Contraceptive Injection 150. It also has 31% less hormone and is given under your skin, and not into your muscle.

What are the most serious risks of depo-subQ provera 104?

Losing calcium from your bones. depo-subQ provera 104 use may decrease the amount of calcium in your bones. The longer you use depo-subQ provera 104, the more calcium you are likely to lose. This increases the risk of your bones weakening if you use depo-subQ provera 104 continuously for a long time (for example, if you use depo-subQ provera 104 for more than 2 years). The loss of calcium may increase your risk of osteoporosis and broken bones, particularly after menopause. Calcium is generally added to the bones during teenage years.
The decrease of calcium in your bones is of most concern if you are a teenager or have the following risk factors:

  • Bone disease
  • Anorexia nervosa (an eating disorder)
  • Strong family history of osteoporosis
  • Drug use that can lower the amount of calcium in bones (drugs for epilepsy or steroids)
  • Drinking a lot of alcohol or smoking a lot

Abnormal or very heavy bleeding. If you start having very heavy or very long periods, tell your healthcare provider.

Liver problems. Your healthcare provider may stop depo-subQ provera 104 if you have liver problems. Some signs of liver problems are yellow skin or eyes, feeling like you have the flu, feeling more tired than usual, and itching. Tell your healthcare provider if you have these symptoms.

Allergic reaction. Allergic reactions to depo-subQ provera 104 are not common. If you have hives, problems breathing, or just do not feel right after your shot, call your healthcare provider or go to the Emergency Room right away.

Serious blood clots. Call your healthcare provider immediately if you:

  • Have sharp chest pain, cough blood, or suddenly have trouble breathing
  • Have a sudden severe headache with vomiting, blindness or trouble talking, weakness, or numbness in an arm or leg, or get dizzy or faint
  • Have swelling or severe pain in your leg
Are there any reasons I should not receive depo-subQ provera 104 injections?

You should not receive depo-subQ provera 104 injections if you:

  • Are pregnant or might be pregnant
  • Have any unexplained vaginal bleeding
  • Have or have ever had breast cancer
  • Ever had serious blood clots, such as blood clots in your legs (deep venous thrombophlebitis), lungs (pulmonary embolism), heart, or brain
  • Have liver disease
  • Are allergic to anything in depo-subQ provera 104
    see a list of the ingredients in depo-subQ provera 104

depo-subQ provera 104 is not recommended for long term use (more than 2 years). If other methods of birth control are not right for you, talk to your healthcare provider about the risks of continuing use with depo-subQ provera 104.

Active and inactive ingredients in depo-subQ provera 104

Active ingredient: medroxyprogesterone acetate
Inactive ingredients: methylparaben, propylparaben, sodium chloride, polyethylene glycol, polysorbate 80, monobasic sodium phosphate H2O, dibasic sodium phosphate 12H2O, methionine, povidone, water for shot. When necessary, the pH is adjusted with sodium hydroxide or hydrochloric acid, or both.

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What do I need to tell my healthcare provider before I start taking depo-subQ provera 104?

Tell your healthcare provider about all your medical conditions.

Most important, tell your healthcare provider if you:

  • Are pregnant or might be pregnant—you should not receive depo-subQ provera 104 if you are pregnant
  • Plan to become pregnant in the next year
  • Have a history of cancer
  • Have an abnormal mammogram (breast x-ray), lumps in your breast, or bleeding from your nipples
  • Have irregular, light, or heavy menstrual periods
  • Have or have had any of the following medical problems:
    • Kidney problems
    • High blood pressure
    • Migraine headaches
    • Asthma
    • Seizures
    • Diabetes, or if it runs in your family
    • Depression
    • Heart attack, stroke, or blood clots
    • Bone disease
    • Anorexia nervosa (an eating disorder)
    • A strong family history of osteoporosis
    • Use of drugs for epilepsy or steroids—can lower the amount of calcium in bones
    • Using alcohol excessively or smoking
  • Are taking any medicines including prescription and over-the-counter drugs, vitamins, and herbal products
How will I get depo-subQ provera 104?

You will get a prescription for depo-subQ provera 104 filled at your pharmacy before every appointment. Bring this with you to your healthcare provider. He or she will give you an injection just under the skin on your thigh or belly. You will receive 1 injection about every 3 months.

How does depo-subQ provera 104 prevent pregnancy?

depo-subQ provera 104 stops monthly ovulation by stopping the release of an egg from your ovaries. That way, there’s no egg for sperm to fertilize. So your chances of getting pregnant are very low. The thinning of the endometrial lining is another way that depo-subQ provera 104 prevents pregnancy.

How well does depo-subQ provera 104 work for preventing pregnancy?

When you use depo-subQ provera 104 correctly, the chance of getting pregnant is very low. In studies, no women became pregnant during the year they used depo-subQ provera 104 injections. It has a 97% to 99.7% chance of working, which means it is very effective.

Might depo-subQ provera 104 help relieve pain related to endometriosis?

depo-subQ provera 104 was shown to reduce endometriosis-associated pain in women with the signs and symptoms of endometriosis in 2 active comparator-controlled studies. Both studies assessed reduction in endometriosis-associated pain over 6 months of treatment and recurrence of symptoms for 12 months post-treatment.

How do I use depo-subQ provera 104?

You don’t actually “use” depo-subQ provera 104. It is an injection that will be given to you by your healthcare provider. So every 12 to 14 weeks, which is about every 3 months, you will go into your doctor’s office to receive your depo-subQ provera 104 injection. This may be an option for you if you can’t take daily birth control.

When do I receive my first shot?

Your healthcare provider will want to be sure that you are not pregnant before you get your first shot. Normally, you get the shot by the fifth day from the START of your menstrual period. You get it whether or not you are still bleeding.

If you are breastfeeding, you may have your first shot as early as 6 weeks after you deliver your baby.

After I receive my first shot, is there anything I need to keep in mind?

It is very important to keep getting depo-subQ provera 104 every 3 months. If you wait more than 14 weeks between shots, you could become pregnant. Your healthcare provider must make sure you are not pregnant before you get your next shot.

What if I miss a shot?

If you miss a shot, or wait longer than 14 weeks between shots, you could get pregnant. The longer you wait, the greater the risk of getting pregnant.

  • Talk with your healthcare provider to find out when to restart depo-subQ provera 104. You should be tested to be sure you are not pregnant
  • Use another kind of nonhormonal birth control, such as condoms, until you start depo-subQ provera 104 again
What are common side effects of depo-subQ provera 104?

The most common side effects are:

  • Changes in your monthly periods. You may not know when you will bleed, your periods may not be regular, you may have heavy bleeding, or you may have spotting. You may have more days of bleeding during the first 2 or 3 months after you start depo-subQ provera 104. Over time, you may have less and less bleeding. Many women stop having periods by the end of 1 year. Your periods will come back eventually after you stop using depo-subQ provera 104
  • Weight gain. In studies, women gained an average of 3 to 4 pounds during the first year they used depo-subQ provera 104. After 2 years of using depo-subQ provera 104, women gained an average of 7 to 8 pounds. Some women gained more, some gained less, some lost, and some stayed the same. Weight changes beyond 2 years of use with depo-subQ provera 104 have not been studied. Women who used a similar birth control product for 5 years gained on average 5 pounds more than women who did not use a hormone contraceptive product
  • Skin reaction where you got the shot. Lumps, skin dimpling, or pain are usually mild and usually don’t last long. Scarring is unusual, but may happen. If there is swelling or your skin gets hot, has pus, or looks bruised 1 or more days after your shot, call your healthcare provider
  • Headache

Women using depo-subQ provera 104 for birth control or endometriosis had these less common side effects: abdominal pain, acne, breast tenderness, being irritable, depression, hot flushes, insomnia, joint pain, lack of energy, less sex drive, nausea, and sleepiness.

If you feel you are having other side effects, talk with your healthcare provider.

Does depo-subQ provera 104 cause cancer?

  • Birth control like depo-subQ provera 104 was studied in women for many years. In general, the risk of breast cancer slightly increased or stayed about the same as in women not using birth control like depo-subQ provera 104
  • The risk of cancer of the ovary, liver, or cervix did not change
  • There is a decreased risk of cancer of the uterus (endometrial cancer)
Why do more than half of women on depo-subQ provera 104 stop getting their periods?

depo-subQ provera 104 causes a thinning of the endometrial lining. The shedding of this lining is called menstruation. This is also known as a woman’s “period.” When the lining is thin, there is nothing to shed. This is why more than half of women may stop having periods altogether on depo-subQ provera 104.

If I stop getting my period, will it ever come back again?

Yes. When you no longer receive depo-subQ provera 104 injections, your periods should eventually come back.

What if I want to get pregnant?

The effect of depo-subQ provera 104 can last for a long time after you stop getting shots. Although you may be able to get pregnant quickly, it is more likely to take a year or longer after your last shot before you get pregnant.

Where can I get general advice about depo-subQ provera 104?

For more information about depo-subQ provera 104, ask your healthcare provider or pharmacist.

Is there any way I can save money on my prescriptions?

Yes! Pfizer will give you a coupon you can print out at home and take with you every time you go to the pharmacy to get your prescription. You can save up to $20 on your prescription. Make sure you find out more by clicking below.

Find out how easy it is to print out a coupon for depo-subQ provera 104

INDICATION

depo-subQ provera 104® (medroxyprogesterone acetate injectable suspension 104 mg/0.65 mL) is a drug for birth control. It also helps relieve pain related to endometriosis.

IMPORTANT SAFETY INFORMATION

Using depo-subQ provera 104 may cause you to lose calcium stored in your bones.
The longer you use depo-subQ provera 104, the more calcium you are likely to lose. The lost calcium may not return completely once you stop using depo-subQ provera 104.
Loss of calcium may cause weak, porous bones (osteoporosis) that could increase the risk that your bones might break, especially after menopause. It is not known whether your risk of developing osteoporosis may be greater if you are a teenager when you start to use depo-subQ provera 104.
You should use depo-subQ provera 104 long-term (for example, more than 2 years) only if other methods of birth control are not right for you.
depo-subQ provera 104 does not protect you from HIV (AIDS) and other diseases spread through sex (STDs).

Do not take depo-subQ provera 104 if you are pregnant or might be pregnant, if you have any unexplained vaginal bleeding, have ever had breast cancer, have ever had serious blood clots, such as blood clots in your legs, lungs, heart, or head, have liver disease, or are allergic to anything in depo-subQ provera 104.

In addition to loss of calcium from your bones, other serious risks include abnormal or very heavy bleeding, liver problems, and allergic reactions such as hives, problems breathing, or not feeling right after the shot. If you have sharp chest pain, cough blood, suddenly have trouble breathing, have a sudden severe headache with vomiting, blindness, trouble talking, weakness, numbness in an arm or leg, get dizzy or faint, or have swelling or severe pain in your leg, you may have a serious blood clot and should call your healthcare provider immediately.

The most common side effects with depo-subQ provera 104 are changes in your monthly period, weight gain of an average of 3 to 4 pounds during the first year, a skin reaction where you got the shot, and headache.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

For Patient Information for depo-subQ provera 104, click here.
For Full Prescribing Information for depo-subQ provera 104, click here.

*
This coupon will only be accepted at participating pharmacies. These savings are good when presented with a valid, signed prescription for depo-subQ provera 104. Coupon is limited to up to $20. The coupon is not health insurance. No membership fees. Limit 1 Savings Coupon per customer. Offer valid through 07/31/2012. For any questions, please call Customer Service at 1-888-296-1807. Pfizer Inc 235 East 42nd Street, New York, NY 10017 www.pfizer.com

Important Safety Information

Using depo-subQ provera 104 may cause you to lose calcium stored in your bones.
The longer you use depo-subQ provera 104, the more calcium you are likely to lose. The lost calcium may not return completely once you stop using depo-subQ provera 104.
Loss of calcium may cause weak, porous bones (osteoporosis) that could increase the risk that your bones might break, especially after menopause. It is not known whether your risk of developing osteoporosis may be greater if you are a teenager when you start to use depo-subQ provera 104.
You should use depo-subQ provera 104 long-term (for example, more than 2 years) only if other methods of birth control are not right for you.
depo-subQ provera 104 does not protect you from HIV (AIDS) and other diseases spread through sex (STDs).

Do not take depo-subQ provera 104 if you are pregnant or might be pregnant, if you have any unexplained vaginal bleeding, have ever had breast cancer, have ever had serious blood clots, such as blood clots in your legs, lungs, heart, or head, have liver disease, or are allergic to anything in depo-subQ provera 104.

In addition to loss of calcium from your bones, other serious risks include abnormal or very heavy bleeding, liver problems, and allergic reactions such as hives, problems breathing, or not feeling right after the shot. If you have sharp chest pain, cough blood, suddenly have trouble breathing, have a sudden severe headache with vomiting, blindness, trouble talking, weakness, numbness in an arm or leg, get dizzy or faint, or have swelling or severe pain in your leg, you may have a serious blood clot and should call your healthcare provider immediately.

The most common side effects with depo-subQ provera 104 are changes in your monthly period, weight gain of an average of 3 to 4 pounds during the first year, a skin reaction where you got the shot, and headache.